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J. David Gladstone Institutes : ウィキペディア英語版
Gladstone Institutes

The Gladstone Institutes are an independent and nonprofit biomedical research organization whose focus is to better understand, prevent, treat and cure cardiovascular, viral and neurological conditions such as heart failure, HIV/AIDS and Alzheimer's disease.〔(Gladstone boosts funding, science and fame, ''San Francisco Business Times'' )〕 Gladstone researchers study these diseases using techniques of basic and translational science.〔http://www.bizjournals.com/sanfrancisco/blog/biotech/2012/07/gladstone-roddenberry-hiv-alzheimers.html〕 Another focus at Gladstone is building on the breakthrough development of induced pluripotent stem cell technology by one of its investigators, 2012 Nobel Laureate Shinya Yamanaka, to improve drug discovery, personalized medicine and tissue regeneration.〔(Gladstone to announce new stem cell center, ''San Francisco Chronicle'' )〕
Founded in 1979, Gladstone is affiliated with the University of California, San Francisco (UCSF) and is located in San Francisco, adjacent to UCSF’s Mission Bay campus. Approximately 450 staff members—including more than 300 scientists—work at Gladstone.〔(Official Website )〕
== History ==
The Gladstone Institutes was founded in 1979 as a research and training facility housed at San Francisco General Hospital. Under the leadership of Robert Mahley〔(Profile, J. David Gladstone Institutes, ''San Francisco Business Times'' )〕—a leading cardiovascular scientist recruited from the National Institutes of Health〔(Profile of Robert W. Mahley, ''Proceedings of the National Academy of Sciences'' )〕—the J. David Gladstone Institutes was launched with a trust valued at $8 million from the late commercial real estate developer, J. David Gladstone.〔(【引用サイトリンク】url=http://gladstoneinstitutes.org/about-us/the-gladstone-trust/history )
In 1991 Gladstone expanded its focus to include virology and immunology in response to the growing HIV/AIDS crisis.〔
In 1998 Gladstone founded a third institute dedicated to studying neurological diseases.〔
In 2004 the Gladstone Institutes moved to the new facility that it built on San Francisco’s Mission Bay campus.〔(Boost for biotech in SF, ''San Francisco Chronicle'' )〕 Two years later Gladstone founded a center dedicated to translating its biological discoveries into therapies.〔http://gladstoneinstitutes.org/our-science/translational-research〕 Three years later and together with Taube Philanthropies and the Koret Foundation, Gladstone founded the Taube-Koret Center for Huntington's Disease Research,〔http://gladstoneinstitutes.org/our-science/translational-research/centers〕 as a direct outgrowth of the growing focus on translational science to study and find treatments for disease.
In 2010, Dr. Mahley stepped down in order to return to more active research. That same year, R. Sanders “Sandy” Williams left Duke University, where he had been Dean of the School of Medicine—as well as Senior Vice Chancellor and Senior Advisor for International Strategy—to become Gladstone’s new president.〔(Williams spins science into fundraising gold, ''San Francisco Business Times'' )〕
The following year, the S.D. Bechtel, Jr. Foundation helped launch the Center for Comprehensive Alzheimer's Disease Research, while the Roddenberry Foundation helped launch the Roddenberry Stem Cell Center for Biology and Medicine.〔 Also in 2011, the independent and philanthropic Gladstone Foundation formed with the mission of expanding the financial resources that drive Gladstone’s mission.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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